Fig. 8From: Advanced 4-dimensional cone-beam computed tomography reconstruction by combining motion estimation, motion-compensated reconstruction, biomechanical modeling and deep learningThe envisioned future developments towards real-time 4D-CBCT imaging, by combining real-time on-board information provided by non-ionizing imaging signals including the optical surface imaging, and prior information (prior CT/CBCT, prior motion model), and real-time on-board x-ray imaging. Through combining all these information sources, a reconstruction system comprising SMEIR, biomechanical modeling, and AI could potentially achieve real-time imaging to guide the most accurate treatment delivery, and allow on-the-fly plan adjustment to fit the patients’ daily variations. 4D-CBCT: 4-Dimensional cone-beam computed tomography; SMEIR: Simultaneous motion estimation and image reconstruction; AI: Artificial intelligenceBack to article page